Hypo-cholesterolemient
Anti-fungal
Anti-cancerous
Anti-hystaminic
CRISTALLISATION of an API can be performed using supercritical CO2 as solvent (RESS Process) or as an antisolvant ( SAS Process).
These processes lead to fine powder with a narrow size distribution. It can also be used in co-process with excipients to obtain composite particles.
The different goals usually searched are :
- The obtention of a specific polymorph
- Micronisation of particles below 1µm
- Enhancement of API's specific surface area
- Obtention of dry particle (RESS Process)
- Particle design for special administration form