Cristallisation - Hypo-cholesterolemient

Hypo-cholesterolemient

Cristallisation - Anti-fungal

Anti-fungal

Cristallisation - Anti-cancerous

Anti-cancerous

Cristallisation - Anti-hystaminic

Anti-hystaminic

CRISTALLISATION of an API can be performed using supercritical CO2 as solvent (RESS Process) or as an antisolvant ( SAS Process).

These processes lead to fine powder with a narrow size distribution. It can also be used in co-process with excipients to obtain composite particles.

The different goals usually searched are :

  • The obtention of a specific polymorph
  • Micronisation of particles below 1µm
  • Enhancement of API's specific surface area
  • Obtention of dry particle (RESS Process)
  • Particle design for special administration form